Thermo Fisher Scientific CD200 Monoclonal Antibody (OX-2)
Rat 시료에서 CD200/OX-2 단백질을 검출하는 Mouse IgG1 단일클론 항체. Flow cytometry, immunoprecipitation, immunofluorescence에 적합. Protein G로 정제된 액상형 제품으로 4°C 보관 권장. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | Assay-dependent |
| Flow Cytometry (Flow) | 1 µg/1 million cells |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OX-2 |
| Immunogen | Rat thymocyte membrane glycoproteins |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1075401 |
Additional Formats
Product Specific Information
MA1-70035 detects CD200/OX-2 in rat samples.
It has been successfully used in flow cytometry, immunoprecipitation, and immunofluorescence procedures.
The immunogen is rat thymocyte membrane glycoproteins.
Target Information
CD200 is a type-1 membrane glycoprotein belonging to the immunoglobulin superfamily, containing two immunoglobulin domains. It interacts with CD200R on myeloid cells, helping to prevent macrophage activation.
Homologues exist in herpesviruses and poxviruses. Studies in rodents indicate CD200 regulates myeloid cell activity and provides inhibitory signals to macrophages.
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Diseases associated with CD200 dysfunction include Mantle Cell Lymphoma and Primary Hypertrophic Osteoarthropathy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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