Thermo Fisher Scientific ITGA3 Monoclonal Antibody (J143)
인간 ITGA3 단백질을 인식하는 Mouse IgG1 단클론 항체로, IHC(F), ICC/IF, ELISA에 사용 가능. 비결합형 액상 형태이며 4°C 단기, -20°C 장기 보관 권장. 신장 조직을 양성 대조로 추천.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (Frozen) (IHC (F)) | 1:40 | - |
| Immunocytochemistry (ICC/IF) | 1:40 | - |
| ELISA | - | View 1 publication |
Product Specifications
| Item | Description |
|---|---|
| Published species | Human |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | J143 |
| Immunogen | 253J bladder cancer cell line |
| Conjugate | Unconjugated |
| Form | Liquid |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_779709 |
Product Specific Information
Recommended positive controls: Kidney.
Target Information
ITGA3 (INTEGRIN, ALPHA-3), also called CD49C, VLA3 or GAPB3, is a protein encoded by the ITGA3 gene in humans.
ITGA3 is an integrin alpha subunit and a member of the cell surface adhesion molecule family.
It is mapped to chromosome 17 (17q21.33) and forms half of the alpha3beta1 integrin duplex, which plays a role in neural migration and corticogenesis together with the beta-1 subunit.
A functional link between DAB1 phosphorylation and ITGA3 signaling drives the timely detachment of migrating neurons from radial glial fibers.
Expression of human ITGA3 increases virus infectivity for Chinese hamster ovary cells.
ITGA3 contains 13 potential N-glycosylation sites, 2 potential cleavage sites, and 7 N-terminal repeating units characteristic of ITGAs.
Recombinant ITGA3 is expressed as a 150-kD protein, similar in size to the native protein by western blot analysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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