Thermo Fisher Scientific EpoR VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA0954)
Recombinant alpaca monoclonal antibody targeting human EpoR, expressed in CHO cells. Compatible with direct ELISA. Purified by metal-chelate chromatography, supplied in PBS without preservative. Suitable for research use only.
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Applications
- ELISA (ELISA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA0954 |
| Immunogen | Recombinant Human EPOR |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
EpoR encodes the erythropoietin receptor, a member of the cytokine receptor family. When erythropoietin binds to this receptor, it activates Jak2 tyrosine kinase, which triggers intracellular signaling pathways such as Ras/MAP kinase, phosphatidylinositol 3-kinase, and STAT transcription factors. Activated EpoR supports erythroid cell survival. Mutations in the EPOR gene may lead to erythroleukemia and familial erythrocytosis, and dysregulation can influence tumor growth. Multiple transcript variants are generated through alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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