Thermo Fisher Scientific PSMA VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1352)
Thermo Fisher Scientific의 PSMA VHH-8His-Cys-tag 재조합 알파카 단일클론 항체. 인간 PSMA(FOLH1) 인식용으로 ELISA 및 SPR에 적합. CHO 세포에서 발현된 VHH 형식 항체로, 금속 킬레이트 크로마토그래피로 정제. 연구용으로만 사용 가능.
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Applications
ELISA (ELISA)
- Tested Dilution: Assay-dependent
Surface Plasmon Resonance (SPR)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1352 |
| Immunogen | Recombinant Human FOLH1/PSMA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
This gene encodes a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on various substrates, including folate and N-acetyl-L-aspartyl-L-glutamate. It is expressed in tissues such as prostate, central and peripheral nervous system, and kidney. Mutations may cause impaired folate absorption, leading to low blood folate levels and hyperhomocysteinemia. Expression in the brain may be involved in conditions associated with glutamate excitotoxicity. In the prostate, the protein is up-regulated in cancerous cells and serves as a diagnostic and prognostic marker for prostate cancer. The gene likely arose from a duplication event, and alternative splicing yields multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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