Thermo Fisher Scientific POLR2K Polyclonal Antibody
POLR2K 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체로, Western blot에 사용 가능. 인간 및 생쥐 반응성. 액상 형태로 1 mg/mL 농도, PBS와 글리세롤 버퍼에 보관. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human POLR2K (Accession P53803), corresponding to amino acid residues T3–V53 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2853138 |
Product Specific Information
Antibody detects endogenous levels of total RPAB4.
Target Information
RNA polymerase II (Pol II) is a multi-subunit enzyme responsible for the transcription of protein-coding genes. Transcription initiation requires recruitment of the complete transcription machinery to a promoter via activators and chromatin remodeling factors. Pol II can coordinate 10 to 14 subunits, interacting with promoter regions and various transcription factors.
POLR2K (polymerase (RNA) II (DNA directed) polypeptide K), also known as RPB12, RPABC4, RPB7.0, hRPB7.0, hsRPB10a, RPB10alpha, or ABC10-alpha, is a 58 amino acid nuclear protein belonging to the archaeal rpoP/eukaryotic RPC10 RNA polymerase subunit family. The gene encoding POLR2K is located on human chromosome 8, which spans approximately 146 million base pairs, contains over 800 genes, and is associated with various diseases and malignancies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일: PA5-103805_POLR2K_P53803-1_Rabbit_PDP.jpeg)
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