Thermo Fisher Scientific POLR2K Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Product Specifications

Species Reactivity

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human POLR2K(Accession P53803), corresponding to amino acid residues T3-V53. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:POLR2K,uniProtId:P53803-1,ncbiNodeId:9606,antigenRange:3-53,antigenLength:58,antigenImageFileName:PA5-103805_POLR2K_P53803-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103805_POLR2K_P53803-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2853138

Product Specific Information

Antibody detects endogenous levels of total RPAB4.

Target Information

RNA polymerase II (Pol II) is a multi-subunit enzyme responsible for the transcription of protein-coding genes. Transcription initiation requires recruitment of the complete transcription machinery to a promoter via solicitation by activators and chromatin remodeling factors. Pol II can coordinate 10 to 14 subunits. This complex interacts with the promoter regions of genes and a variety of elements and transcription factors. POLR2K (polymerase (RNA) II (DNA directed) polypeptide K), also known as RPB12, RPABC4, RPB7.0, hRPB7.0, hsRPB10a, RPB10alpha or ABC10-alpha, is a 58 amino acid nuclear protein belonging to the archaeal rpoP/eukaryotic RPC10 RNA polymerase subunit family. The gene encoding POLR2K is located on human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.