Thermo Fisher Scientific Human ASAH1 Synthetic Peptide
인간 ASAH1 단백질의 카복시 말단 16개 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20574의 블로킹 펩타이드로 사용 가능. 정제된 액상 형태로 제공되며, PBS 버퍼에 0.1% BSA와 0.02% sodium azide를 포함. 연구용으로만 사용.
- 카탈로그번호
- PEP0694
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Human ASAH1 Synthetic Peptide
Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the carboxy terminus of human ASAH1.
PEP-0694 can be used as a blocking peptide with polyclonal antibody PA5-20574.
Target Information
ASAH1 encodes a member of the acid ceramidase family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. The processing of this preproprotein generates alpha and beta subunits that heterodimerize to form the mature lysosomal enzyme, which catalyzes the degradation of ceramide into sphingosine and free fatty acid.
This enzyme is overexpressed in multiple human cancers and may play a role in cancer progression. Mutations in this gene have been linked to the lysosomal storage disorder Farber lipogranulomatosis and the neuromuscular disorder spinal muscular atrophy with progressive myoclonic epilepsy. Related pathways include Innate Immune System and Sphingolipid metabolism. Diseases associated with ASAH1 include Farber Lipogranulomatosis and Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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