Thermo Fisher Scientific CYP1A1 Polyclonal Antibody, DyLight 488
DyLight 488 형광 표지된 CYP1A1 폴리클로날 항체로 인간 시료에 반응하며, Flow Cytometry에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 신뢰성 제공. 4°C 암소 보관, 연구용으로만 사용.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1–3 µg/1x10^6 cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E.coli-derived human CYP1A1 recombinant protein (Position: H183–D320) |
| Conjugate | DyLight™ 488 |
| Excitation / Emission Max | 492 / 519 nm |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746242 |
Target Information
The CYP1A1 gene encodes a member of the cytochrome P450 superfamily of enzymes. These monooxygenases catalyze reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids.
This protein localizes to the endoplasmic reticulum and is induced by polycyclic aromatic hydrocarbons (PAHs), including those found in cigarette smoke.
Although its endogenous substrate is unknown, CYP1A1 can metabolize some PAHs into carcinogenic intermediates and has been associated with lung cancer risk.
A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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