Thermo Fisher Scientific DDX39B Monoclonal Antibody (OTI2F11), TrueMAB
DDX39B 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI2F11). Western blot 및 IHC(P)에서 검증됨. 다양한 종(Dog, Human, Mouse, Rat 등)에 반응. Lyophilized 형태로 제공되며, 재구성 후 1 mg/mL 농도. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F11 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 319–428 of human DDX39B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The DDX39B gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing.
This protein is an essential splicing factor required for the association of U2 small nuclear ribonucleoprotein with pre-mRNA and also plays a key role in mRNA export from the nucleus to the cytoplasm.
A cluster of genes (BAT1–BAT5) is located near TNF alpha and TNF beta genes within the human MHC class III region.
Mutations in DDX39B may be associated with rheumatoid arthritis.
Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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