Thermo Fisher Scientific DDX39B Monoclonal Antibody (OTI2F11), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:500

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:500

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, it is recommended to perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

The DDX39B gene encodes a member of the DEAD box family of RNA-dependent ATPases that mediate ATP hydrolysis during pre-mRNA splicing.
This protein is an essential splicing factor required for the association of U2 small nuclear ribonucleoprotein with pre-mRNA and also plays a key role in mRNA export from the nucleus to the cytoplasm.
A cluster of genes (BAT1–BAT5) is located near TNF alpha and TNF beta genes within the human MHC class III region.
Mutations in DDX39B may be associated with rheumatoid arthritis.
Alternatively spliced transcript variants encoding the same protein have been described.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.