Thermo Fisher Scientific MMP11 Monoclonal Antibody (OTI3E10), TrueMAB
Human MMP11 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 적합. Lyophilized 형태로 제공되며, PBS buffer에 trehalose 포함. 재구성 및 결합 실험에 적합하며, 연구용으로만 사용 가능.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3E10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 239-488 of human MMP11 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Stromelysin (MMP-11) is a matrix metalloproteinase with broad substrate specificity, capable of degrading proteoglycan, fibronectin, laminin, casein, and nonhelical collagen regions.
The stromelysin-3 (MMP-11) gene is expressed specifically in stromal cells surrounding invasive breast carcinomas and is localized to chromosome 22q.
MMP-11 expression is more prominent in malignant tumors than in benign ones.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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