Thermo Fisher Scientific DDX39B Monoclonal Antibody (OTI2C12), TrueMAB
DDX39B 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot에 적합합니다. 인간, 마우스, 랫, 개, 비인간 영장류 반응성을 가지며, 동결건조 형태로 제공됩니다. 연구용으로만 사용되며, RNA 스플라이싱 및 mRNA 수출 연구에 활용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 319–428 of human DDX39B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
DDX39B encodes a DEAD box RNA-dependent ATPase essential for pre-mRNA splicing and mRNA export from the nucleus to the cytoplasm. It facilitates the association of U2 small nuclear ribonucleoprotein with pre-mRNA. The BAT1–BAT5 gene cluster, including DDX39B, is located near TNFα and TNFβ genes within the human MHC class III region. Mutations may be linked to rheumatoid arthritis. Alternatively spliced transcript variants encoding the same protein have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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