Thermo Fisher Scientific POU6F1 Polyclonal Antibody
POU6F1 단백질을 인식하는 Thermo Fisher Scientific의 goat polyclonal 항체. Western blot에 최적화되어 있으며 인간과 생쥐 반응성. 고순도 액상 형태로 제공되며 BSA와 sodium azide 포함. 연구용으로만 사용 가능.
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Thermo Fisher Scientific POU6F1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 0.3–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-ETPTVSQLVSKPHTP, from the internal region of POU6F1 (aa 121–135) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2554492 |
Product Specific Information
- Predicted to react with rat, dog, and cow based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
Brn-5 (Brain-5), also known as POU6F1, MPOU, or TCFB1, is widely expressed but during embryogenesis is exclusively found in the developing brain and spinal cord.
It contains two DNA-binding domains: the POU-specific domain and the POU homeodomain, each with an HTH (helix-turn-helix) motif.
Brn-5 binds to CRH (corticotrophin-releasing hormone) elements with high affinity and can enhance Prolactin gene expression and activate Pit-1 expression.
Usage Note
For Research Use Only. Not for use in diagnostic procedures.
Not for resale without express authorization.
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