Thermo Fisher Scientific SIRT5 Recombinant Rabbit Monoclonal Antibody (JJ084-01)
SIRT5 단백질을 인식하는 재조합 토끼 단일클론 항체로, Western blot에 최적화되어 있습니다. HEK293 세포에서 발현되며 높은 특이성과 일관된 품질을 제공합니다. 단백질 A로 정제된 액상 형태이며, 장기 보관 시 -20°C에서 안정적입니다.
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Applications
- Western Blot (WB): 1:1,000–1:2,000
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | JJ084-01 |
| Immunogen | Recombinant protein within Human SIRT5 (aa 1–160) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | TBS, pH 7.4, with 40% Glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2809741 |
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The DNA sequences encoding immunoreactive rabbit antibodies are cloned and screened to select optimal candidates.
Advantages include:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broader immunoreactivity due to large rabbit immune repertoire
Target Information
SIRT5 is a member of the sirtuin family (Sir2-like proteins) found in both prokaryotes and eukaryotes. These proteins share a conserved core domain with sequence motifs across species. Sirtuins metabolize NAD and may function as mono-ADP-ribosyltransferases.
Recent findings suggest a coupled activation mechanism between Sir2-mediated NAD metabolism and histone deacetylation, indicating complex regulatory roles in cellular metabolism.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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