Thermo Fisher Scientific Chitotriosidase Polyclonal Antibody
인간 Chitotriosidase 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 IHC(P) 실험에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공. 연구용으로만 사용되며 Gaucher 병 관련 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CHIT1. Recombinant protein control fragment (Product #RP-90229) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2789554 |
Product Specific Information
Immunogen sequence:
FDDVESFKTK VSYLKQKGLG GAMVWALDLD DFAGFSCNQG RYPLIQTLRQ ELSLPYLPSG TPELEVPKPG QPSEPEHGPS PGQDTFCQGK ADGLYPNPRE RSSFYSCAAG RLFQQSCPTG LVFSNSCKCC TWN
Target Information
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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