Thermo Fisher Scientific CD354 (TREM-1) Monoclonal Antibody (L5-B8.2A12.3A12), PE
Mouse TREM-1 단백질을 인식하는 Rat 모노클론 항체로, PE 형광 표지되어 Flow Cytometry에 적합. 단백질 G로 정제된 동결건조 형태이며, 재구성 후 사용. 염증 반응 연구 및 면역세포 활성 분석에 유용.
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Applications
- Flow Cytometry (Flow): Neat
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | L5-B8.2A12.3A12 |
| Immunogen | Mouse TREM-1 Fc fusion protein |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Lyophilized |
| Concentration | Not Determined |
| Purification | Protein G |
| Storage Buffer | PBS with 1% BSA, 5% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, store in dark, DO NOT FREEZE! |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2745191 |
Additional Formats
Product Specific Information
Reconstitute with 1.0 mL distilled water.
Rat anti-Mouse TREM-1 antibody, clone L5-B8.2A12.3A12 recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30 kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes.
Target Information
TREM1 (triggering receptor expressed on myeloid cells 1) is a receptor belonging to the Ig superfamily that amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections. It stimulates release of pro-inflammatory chemokines and cytokines and increases surface expression of cell activation markers. TREM1 and related proteins such as TREM2 modulate the inflammatory response. TREM1 has been linked to inflammatory bowel disease, resulting in enhanced production of TNF, IL-6, IL-8, and MCP-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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