Thermo Fisher Scientific Bacillus anthracis Lethal Factor Monoclonal Antibody (BAL0106)
Bacillus anthracis의 치사 인자(Lethal Factor)를 검출하는 Mouse IgG1 단클론 항체입니다. ELISA 등 다양한 분석에 사용 가능하며, 단백질 G로 정제된 액상 형태입니다. 4°C에서 보관하며, 연구용으로만 사용됩니다.
- 카탈로그번호
- MA122669
- 판매단위
- pk
카탈로그
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Thermo Fisher Scientific Bacillus anthracis Lethal Factor Monoclonal Antibody (BAL0106)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bacteria |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | BAL0106 |
| Immunogen | Highly purified lethal factor antigen of Bacillus anthracis |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_557702 |
Product Specific Information
MA1-22669 detects Bacillus anthracis lethal factor in bacterial samples.
Target Information
Anthrax toxin is a three-protein exotoxin secreted by virulent strains of Bacillus anthracis, the causative agent of anthrax. It is composed of:
- Protective antigen (PA): a cell-binding protein
- Edema factor (EF) and Lethal factor (LF): enzyme components
These components assemble and are endocytosed by target cells. In the endosome, LF and EF translocate into the cytoplasm, disrupting immune cell signaling, migration, and potentially inducing cell lysis, particularly in macrophages. Anthrax toxin enables the bacteria to evade immune defenses, proliferate, and cause host death.
Research on anthrax toxin provides insights into macromolecular assembly, protein translocation, pore formation, and endocytosis mechanisms.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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