Thermo Fisher Scientific AVPR2 Polyclonal Antibody
AVPR2 단백질을 인식하는 Rabbit Polyclonal 항체로, IHC(P)에서 검증됨. Human, Mouse, Rat 등 다양한 종에 반응. 항원 친화 크로마토그래피로 정제된 액상 항체. 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 26 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Hamster, Human, Mouse, Non-human primate, Rabbit, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 20 amino acid peptide from 3rd cytoplasmic domain of human AVPR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550731 |
Product Specific Information
Percent identity with other species by BLAST analysis:
Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Rabbit (100%).
Target Information
Avpr2 is a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone synthesized in the supraoptic and paraventricular nuclei of the hypothalamus. It is transported in neurosecretory vesicles to the neurohypophysis, where it is stored or secreted into the bloodstream.
Avpr2 exerts direct antidiuretic action on the kidney and causes vasoconstriction of peripheral vessels. It can contract smooth muscle during parturition and lactation and is involved in cognition, tolerance, adaptation, and complex sexual and maternal behavior, as well as regulation of water excretion and cardiovascular functions. The activity of Avpr2 is mediated by G proteins that activate adenylate cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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