Thermo Fisher Scientific AVPR2 Polyclonal Antibody
Rabbit polyclonal antibody recognizing AVPR2 protein. Validated for IHC (Paraffin) with 3–6 µg/mL dilution. Reacts with human and non-human primates. Supplied as liquid, 1 mg/mL in PBS with 0.1% sodium azide. Suitable for research use only.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 3–6 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic 15 amino acid peptide from C-terminus of human AVPR2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.1% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2550732 |
Product Specific Information
Percent identity with other species by BLAST analysis:
- Human, Gorilla, Gibbon, Baboon, Monkey (100%)
- Marmoset, Panda (87%)
- Dog (80%)
Target Information
Avpr2 is a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone synthesized in the supraoptic and paraventricular nuclei of the hypothalamus. Together with neurophysin 2, it is packaged into neurosecretory vesicles and transported to the neurohypophysis, where it is stored or secreted into the bloodstream.
Avpr2 has antidiuretic action on the kidney and causes vasoconstriction of peripheral vessels. It also contributes to smooth muscle contraction during parturition and lactation and is involved in cognition, adaptation, and regulation of water excretion and cardiovascular functions. Its activity is mediated by G proteins that activate adenylate cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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