Thermo Fisher Scientific ARG Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: 2–5 µg/mg lysate

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Mouse

Target Information

ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and/or cytoskeletal reorganization. Abl2 encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to ABL1, including the tyrosine kinase, SH2, and SH3 domains, and plays a role in cytoskeletal rearrangements via its C-terminal F-actin and microtubule-binding sequences. Abl2 is expressed in both normal and tumor cells and is involved in translocation with the ETV6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.