Thermo Fisher Scientific BTLA Monoclonal Antibody (OTI7G4), TrueMAB

Applications

Flow Cytometry (Flow)

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

• Reconstitution: Add 100 µL distilled water to achieve ~1 mg/mL concentration.
• For conjugation experiments, perform additional desalting (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).

Target Information

BTLA (B and T-lymphocyte attenuator) is a member of the CD28 superfamily of co-inhibitory receptors. It functions as a lymphocyte inhibitory receptor that suppresses immune responses. BTLA is constitutively expressed on most CD4+ and CD8+ T cells, with expression decreasing upon activation. It remains expressed on Th1 cells but not Th2 cells. BTLA interacts with the TNFR family member HVEM, forming a key pathway regulating lymphocyte activation and homeostasis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.