Thermo Fisher Scientific ABH1 Polyclonal Antibody
ABH1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. Western blot에 최적화되어 있으며 Human에 반응. 항원 친화 크로마토그래피로 정제, 1 mg/mL 농도. 연구용으로 DNA 손상 복구 관련 연구에 적합.
- 카탈로그번호
- PA522376
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 166–387 of ABH1 (Uniprot ID: Q13686) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11153474 |
Product Specific Information
- Recommended positive controls: HeLa, NT2D1
- Predicted reactivity: Mouse (90%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It reverses damage by oxidative demethylation of 1-methyladenine and 3-methylcytosine.
This dioxygenase repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate, and iron.
May play a role in placental trophoblast lineage differentiation. Exhibits DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single- and double-stranded DNA at abasic sites, with greatest activity toward double-stranded DNA with two abasic sites.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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