Thermo Fisher Scientific ALDH1A2 Polyclonal Antibody
ALDH1A2 단백질을 인식하는 Rabbit Polyclonal 항체로, Human, Mouse, Rat에 반응합니다. Western blot, IHC, ICC/IF에 사용 가능하며 항원 친화 크로마토그래피로 정제되었습니다. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:1,000 |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 278–518 of ALDH1A2 (Uniprot ID: O94788) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.43 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol, 1% BSA |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_11154097 |
Product Specific Information
- Recommended positive controls: IMR32, mouse liver, mouse testis, rat testis
- Predicted reactivity: Mouse (97%), Rat (98%), Xenopus laevis (91%), Dog (99%), Chicken (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This protein belongs to the aldehyde dehydrogenase family. The encoded enzyme catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid acts as a hormonal signaling molecule in developing and adult tissues. Studies in mice suggest that this enzyme, together with cytochrome CYP26A1, regulates local embryonic RA levels, contributing to posterior organ development and prevention of spina bifida. Three transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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