Thermo Fisher Scientific NKX2 Monoclonal Antibody (OTI4F1), TrueMAB
NKX2 단백질을 인식하는 Mouse monoclonal antibody (Clone OTI4F1). Western blot에 적합하며 Human, Mouse, Rat 시료에 반응. Lyophilized 형태로 제공되며 PBS buffer와 trehalose 포함. 연구용으로 사용.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4F1 |
| Immunogen | Full length human recombinant protein of human NKX2-1 (NP_003308) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This gene encodes a thyroid-specific transcription factor that binds to the thyroglobulin promoter and regulates expression of thyroid-specific genes. It also influences genes involved in morphogenesis.
Mutations or deletions are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be linked to thyroid cancer.
Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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