Thermo Fisher Scientific EHMT1 Polyclonal Antibody
EHMT1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인간 시료에 반응하며, ICC/IF에 적합. 항원 친화 크로마토그래피로 정제됨. PBS 버퍼와 글리세롤 포함, 4°C 또는 -20°C 보관 권장.
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Thermo Fisher Scientific EHMT1 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Protein corresponding to Human EHMT1. Recombinant protein control fragment (Product #RP-105144). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.15 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2856909 |
Product Specific Information
Immunogen sequence:
ADGETNGSCE NSDASSHANA AKHTQDSARV NPQDGTNTLT RIAENGVSER DSEAAKQNHV TADDFVQTSV IGSNGYILNK PALQAQPLRT TSTLASSLPG HAAKTLPGGA GKGRTPSAFP QTPAAPPATL
Target Information
EHMT1, also known as EUHMTASE1, is a histone methyltransferase that methylates Lys-9 of histone H3 in vitro. H3 Lys-9 methylation serves as an epigenetic transcriptional repression tag by recruiting HP1 proteins to methylated histones. EHMT1 is likely targeted to histone H3 by DNA-binding proteins such as E2F6, MGA, MAX, and DP1. During the G0 phase, it contributes to silencing MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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