Thermo Fisher Scientific EHMT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein corresonding to Human EHMT1. Recombinant protein control fragment (Product #RP-105144). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:EHMT1,uniProtId:Q9H9B1-1,ncbiNodeId:9606,antigenRange:50-179,antigenLength:1298,antigenImageFileName:PA5-111499_EHMT1_Q9H9B1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-111499_EHMT1_Q9H9B1-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.15 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2856909

Product Specific Information

Immunogen sequence: ADGETNGSCE NSDASSHANA AKHTQDSARV NPQDGTNTLT RIAENGVSER DSEAAKQNHV TADDFVQTSV IGSNGYILNK PALQAQPLRT TSTLASSLPG HAAKTLPGGA GKGRTPSAFP QTPAAPPATL

Target Information

EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates Lys-9 of histone H3 in vitro. H3 Lys-9 methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.