Thermo Fisher Scientific OTC Monoclonal Antibody (OTI2C12), TrueMAB
OTC 단백질을 인식하는 마우스 단클론 항체로 Western blot 및 IHC(P) 실험에 적합합니다. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능합니다. 휴먼 OTC 단백질(aa 33-354)을 면역원으로 제작되었습니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-Dependent | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2C12 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 33–354 of human OTC produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
This nuclear gene encodes a mitochondrial matrix enzyme. Mutations (missense, nonsense, frameshift) in this enzyme lead to ornithine transcarbamylase deficiency, resulting in hyperammonemia.
Because the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may also play a role in that disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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