
Thermo Fisher Scientific GTF2B Monoclonal Antibody (OTI1H10), TrueMAB
Thermo Fisher Scientific의 GTF2B Monoclonal Antibody (OTI1H10)은 Human, Mouse, Rat에 반응하는 고특이성 항체입니다. Western blot에 최적화되어 있으며, 무보존제 PBS 버퍼에 동결건조 형태로 제공됩니다. 연구용 단백질 검출 및 결합 실험에 적합합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1H10 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 43–316 of human GTF2B produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
Ubiquitin is a 76 amino acid, highly conserved eukaryotic polypeptide that marks cellular proteins for degradation by the 26S proteasome.
This process regulates protein concentration by limiting lifespan through polyubiquitination and involves E1, E2, and E3 enzymes.
Ubiquitination is essential for numerous cellular functions, including:
- Cell cycle and growth regulation
- Embryogenesis and apoptosis
- Signal transduction and DNA repair
- Transcription and replication control
- Stress response and immune functions
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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