Thermo Fisher Scientific CHMP5 Monoclonal Antibody (OTI2E6), TrueMAB
CHMP5 단백질을 인식하는 Mouse IgG1 단일클론 항체. Western blot 및 IHC(P) 검증 완료. 동결건조 형태로 제공되며, 재구성 시 1 mg/mL 농도 권장. 인간, 생쥐, 랫트 반응성. ESCRT-III 복합체 연구용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2E6 |
| Immunogen | Full length human recombinant protein of human CHMP5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CHMP5 belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family.
These proteins are components of the ESCRT-III complex, which is involved in the degradation of surface receptor proteins and formation of endocytic multivesicular bodies.
Some CHMPs localize to both nuclear and cytoplasmic/vesicular regions. CHMP1A, for example, is required for both multivesicular body (MVB) formation and regulation of cell cycle progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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