Thermo Fisher Scientific ABHD13 Polyclonal Antibody
Human ABHD13 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, PBS 버퍼(40% glycerol) 내 액상 형태로 제공. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ABHD13. Recombinant protein control fragment (Product # RP-95842) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2637551 |
Product Specific Information
Immunogen sequence:
KSEGEASEEG LYLDSEAVLD YVMTRPDLDK TKIFLFGRSL GGAVAIHLAS ENSHRISAIM VENTFLSIPH MASTLFSFFP
Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 99%
Target Information
The α/β hydrolase superfamily comprises diverse members involved in important biochemical processes and various diseases. Despite having unrelated sequences and different catalytic activities, they share the canonical α/β hydrolase fold with an eight-stranded parallel α/β structure and a catalytic triad (histidine, acid, nucleophile).
Members of this superfamily are often drug targets for diseases such as diabetes, Alzheimer’s disease, obesity, and blood clotting disorders. The ABHD gene subfamily includes 15 mostly uncharacterized members, most using a serine nucleophile forming the G-X-S-X-G nucleophile elbow.
- ABHD1: Metabolizes smoking xenobiotics
- ABHD2: Involved in atherosclerosis development
- ABHD4: Participates in alternative NAE synthesis pathway
- ABHD5: Mutations linked to Chanarin-Dorfman syndrome
- ABHD6: May play a role in nervous system metabolism and signaling
- ABHD13: 337 amino acid single-pass membrane protein belonging to the ABHD family
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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