Thermo Fisher Scientific Human F1A alpha Synthetic Peptide
인간 F1A alpha 단백질의 C-말단 14개 아미노산 서열 기반 합성 펩타이드. 항체 PA5-19955와 함께 블로킹 펩타이드로 사용 가능. 액상 형태, PBS 버퍼 내 0.1% BSA 및 0.02% sodium azide 포함. -20°C 보관.
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 14 amino acids near the carboxy terminus of human F1A alpha.
PEP-0080 can be used as a blocking peptide with polyclonal antibody PA5-19955.
Target Information
Fas and tumor necrosis factor receptor 1 (TNFR1) are two prototype members in the death receptor family.
A novel protein that associates with the intracellular domains of Fas and TNFR1 was recently identified and designated F1Aalpha and FEM1-b.
F1Aalpha/FEM1-b is the homologue of C. elegans sex determining protein FEM-1. FEM-1/F1Aalpha is cleaved by CED-3 and caspase.
FEM-1/F1Aalpha associates with CED-4 and its mammalian homologue Apaf-1. Overexpression of F1Aalpha induces apoptosis.
F1Aalpha is therefore a novel member of the death receptor associated protein family that mediates apoptosis.
F1Aalpha is expressed in a variety of human and mouse tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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