Thermo Fisher Scientific Mouse RIP3 Synthetic Peptide
마우스 RIP3 단백질의 14개 아미노산 서열로 구성된 합성 펩타이드. RIP3 항체의 블로킹 실험에 사용 가능. 액상 형태로 제공되며 PBS 완충액에 0.1% BSA 포함. -20°C 보관, 연구용으로만 사용.
- 카탈로그번호
- PEP0081
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
Product Specific Information
This peptide corresponds to 14 amino acids of mouse RIP3.
PEP-0081 can be used as a blocking peptide with polyclonal antibody PA5-19956.
Target Information
RIPK3 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, which contains a C-terminal domain unique from other RIP family members. RIPK3 is predominantly localized to the cytoplasm and specifically colocalized in the mitochondrion, which can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. RIPK3 is a component of the tumor necrosis factor (TNF) receptor-I signaling complex and can induce apoptosis and weakly activate the NF-kappaB transcription factor. Caspase-8 prevents RIPK3-dependent necrosis without inducing apoptosis by functioning in a proteolytically active complex with CFLAR, and this complex is required for the protective function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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