Thermo Fisher Scientific CD26 Polyclonal Antibody
CD26(DPP4)에 특이적인 Thermo Fisher Scientific의 goat polyclonal antibody입니다. 인간 시료에 반응하며 IHC와 Flow Cytometry에 사용 가능합니다. 액상 형태로 0.5 mg/mL 농도이며, -20°C에서 보관합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 8 µg/mL |
| Flow Cytometry (Flow) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (PPHFDKSKKYP) corresponding to internal amino acids of DPP4 (aa 532–543) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10984761 |
Product Specific Information
- Predicted to react with canine, human, and mouse based on sequence homology.
- Tested in Peptide ELISA: antibody detection limit dilution 64,000.
Target Information
CD26 (dipeptidyl peptidase IV, DPP IV; adenosine deaminase (ADA) binding protein) is a homodimeric atypical serine protease belonging to the prolyl oligopeptidase family.
CD26 is expressed on lymphocytes and upregulated during T-cell activation, also found on activated B cells, NK cells, and epithelial tissues.
It plays roles in T-cell activation, cell adhesion to extracellular matrix (fibronectin, collagen), and HIV infection.
CD26 is identical to adenosine deaminase complexing protein-2 and functions as a serine exopeptidase cleaving X-proline dipeptides from the N-terminus of polypeptides.
Alterations in CD26 activity are associated with malignant transformation, with enzymatic activity increasing with tumor grade and severity.
Changes in CD26 density have been observed in monocytes and CD4+ T cells during rheumatoid arthritis and systemic lupus erythematosus.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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