Thermo Fisher Scientific SOD3 Polyclonal Antibody
Thermo Fisher Scientific의 SOD3 폴리클로날 항체는 사람, 생쥐, 랫트 시료에서 반응하며 Western blot, IHC, ICC, ELISA에 적합합니다. Rabbit IgG 기반으로 Affinity Chromatography로 정제되었으며, PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| ELISA | 1 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 19–160 of human SOD3 (NP_0030932) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.52 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806721 |
Product Specific Information
- Positive Samples: 22Rv1, HL-60, Mouse kidney, Mouse lung
- Cellular Location: Extracellular space
Immunogen Sequence:
WTGEDSAEPN SDSAEWIRDM YAKVTEIWQE VMQRRDDDGA LHAACQVQPS ATLDAAQPRV TGVVLFRQLA PRAKLDAFFA LEGFPTEPNS SSRAIHVHQF GDLSQGCEST GPHYNPLAVP HPQHPGDFGN FAVRDGSLWR YR
Target Information
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. It is widely expressed in human tissues and shows increased expression in actively dividing cells such as those in testis, thymus, fetal liver, and carcinomas. The encoded protein localizes to the nucleus and promotes stability and nuclear accumulation of transcriptionally active p53, phosphorylating Thr18 and reducing ubiquitination. It may regulate cell proliferation and also phosphorylates histone, casein, and transcription factors ATF2 and c-JUN.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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