Thermo Fisher Scientific GCG Polyclonal Antibody, MaxPab
Glucagon 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot에 최적화되어 있습니다. Human 및 Rat 시료에 반응하며, Affinity chromatography로 정제된 액상 형태입니다. 연구용으로만 사용되며, -20°C 보관을 권장합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific GCG Polyclonal Antibody, MaxPab
Applications
- Western Blot (WB)
Tested Dilution
- 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | GCG (NP_002045.1, 1 a.a. ~ 180 a.a) full-length human protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
MKSIYFVAGL FVMLVQGSWQ RSLQDTEEKS RSFSASQADP LSDPDQMNED KRHSQGTFTS DYSKYLDSRR AQDFVQWLMN TKRNRNNIAK RHDEFERHAE GTFTSDVSSY LEGQAAKEFI AWLVKGRGRR DFPEEVAIVE ELGRRHADGS FSDEMNTILD NLAARDFINW LIQTKITDRK
Target Information
Glucagon is a 29-residue polypeptide hormone (MW 3482), produced in the pancreas.
A related hormone, enteroglucagon (or oxyntomodulin), produced in the mucosa of the small and large intestine, consists of the 29 amino acid sequence of pancreatic glucagon extended by 8 additional residues at the C-terminus.
The biological activities of pancreatic glucagon include:
- Glycogenolysis
- Lipolysis
- Gluconeogenesis
- Ketogenesis
These actions are antagonistic to insulin, leading to increased blood glucose levels.
Immunocytochemical studies have revealed the presence of pancreatic glucagon inside A or alpha cells (15–20% of islet cell population), located at the periphery of human pancreatic islets.
Pathological manifestations of glucagon-type peptide residues are mainly associated with tumors or glucagonomas.
Glucagon-specific antibodies are useful as cell and tumor markers in immunohistochemical applications and as analytical tools for hormone quantification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 없음)
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.