Thermo Fisher Scientific CD1C Monoclonal Antibody (OTI2B3), TrueMAB
인간 CD1C 단백질을 인식하는 Mouse IgG1 단클론 항체로, WB, IHC(P), ICC/IF에 사용 가능. 무보존제, 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도 유지. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B3 |
| Immunogen | Full length human recombinant protein of human CD1C produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
CD1C encodes a member of the CD1 family of transmembrane glycoproteins, structurally related to MHC proteins and forming heterodimers with beta-2-microglobulin.
CD1 proteins present lipid and glycolipid antigens of self or microbial origin to T cells.
Five CD1 family genes are organized in a cluster on chromosome 1.
CD1 family members differ in cellular localization and lipid ligand specificity.
The CD1C protein localizes to late endosomes and lysosomes via a tyrosine-based motif in its cytoplasmic tail and requires vesicular acidification for lipid antigen binding.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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