
Thermo Fisher Scientific MDA5 Polyclonal Antibody
Human MDA5 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western Blot 및 IHC(Paraffin)에 적합. 항원 친화 크로마토그래피로 정제되었으며 PBS/BSA/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:3,000
- Publications: -
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:1,000
- Publications: -
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 217–517 of Human MDA5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 1% BSA, 20% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2545324 |
Product Specific Information
- Recommended positive controls: THP-1, THP-1 (100 ng/mL PMA treatment for 16 hr and 1000 ng/mL LPS treatment for 24 hr)
- Predicted reactivity: Mouse (86%), Rat (86%), Pig (91%), Rhesus Monkey (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
DEAD box proteins are characterized by the conserved motif Asp-Glu-Ala-Asp and a protein kinase C-activating compound, mezerein. Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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