Thermo Fisher Scientific Calmodulin 1/2/3 Polyclonal Antibody
Calmodulin 1/2/3 단백질을 검출하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 시료에 반응하며, 고순도의 Affinity 정제 항체. PBS/glycerol buffer에 보관되며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CALM1 (Accession P0DP23), corresponding to amino acid residues V56–L106 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2851785 |
Product Specific Information
This antibody detects endogenous levels of total Calmodulin 1/2/3.
Target Information
Calmodulin is a small, highly conserved calcium-binding protein found in all eukaryotic cells. It can bind up to four calcium ions and acts as a critical intracellular receptor for regulatory calcium signals. Upon calcium binding, calmodulin undergoes conformational changes that enhance its affinity for target proteins. It functions both directly, by interacting with key target enzymes, and indirectly, via specific kinases. Calmodulin regulates various biological processes including energy and biosynthetic metabolism, cell motility, exocytosis, cytoskeletal assembly, and intracellular modulation of cAMP and calcium concentrations.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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