Thermo Fisher Scientific TRIM22 Monoclonal Antibody (OTI1D3), TrueMAB
인간 TRIM22 단백질(aa 61-406)을 인식하는 마우스 단클론 항체로, WB 및 IHC(P)에서 검증됨. 무보존제, 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도 유지. 인터페론 유도 TRIM22 연구용으로 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 61–406 of human TRIM22 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
TRIM22 is a member of the tripartite motif (TRIM) family, containing three zinc-binding domains (RING, B-box type 1, B-box type 2) and a coiled-coil region.
It localizes to the cytoplasm and its expression is induced by interferon.
TRIM22 down-regulates transcription from the HIV-1 LTR promoter region, suggesting a role in mediating interferon’s antiviral effects.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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