Thermo Fisher Scientific Intelectin 1/Omentin Monoclonal Antibody (ITLN1, 4062)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1–2 µg/mL

Peptide Array (Array)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• Immunohistochemistry (PFA fixed): Incubate antibody for 30 min at room temperature (RT).
• Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at RT for 20 min.

Target Information

ITLN1 has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes.
ITLN1 increases AKT phosphorylation in the absence and presence of insulin.
ITLN1 may play a role in the defense system against microorganisms and may specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner.
It may also be involved in iron metabolism.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.