Thermo Fisher Scientific PSMB7 Monoclonal Antibody (OTI4G9), TrueMAB
PSMB7 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체. Western blot 및 면역세포화학에 적합하며, 인간, 마우스, 랫트, 개 종에 반응. 동결건조 형태로 제공되며, 재구성 후 약 1 mg/mL 농도로 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI4G9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 58–277 of human PSMB7 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure composed of 4 rings of 28 non-identical subunits—2 rings of 7 alpha subunits and 2 rings of 7 beta subunits.
Proteasomes are abundant in eukaryotic cells and cleave peptides in an ATP/ubiquitin-dependent, non-lysosomal pathway.
A modified version, the immunoproteasome, processes class I MHC peptides.
The PSMB7 gene encodes a 20S core beta subunit of the proteasome, part of the proteasome B-type (T1B) family. Expression is downregulated by gamma interferon, and proteolytic processing is required for maturation. This subunit is replaced by catalytic subunit 2i (proteasome beta 10 subunit) in the immunoproteasome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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