Thermo Fisher Scientific DOCK8 Monoclonal Antibody (OTI7H2), TrueMAB
Human DOCK8 단백질(aa 84-405)에 특이적인 Mouse IgG1 단클론 항체. Western blot 및 IHC(P) 적용 가능. Lyophilized 형태로 제공되며 PBS, trehalose buffer에 용해 가능. 항체 재구성 및 결합 실험에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7H2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 84–405 of human DOCK8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step.
Recommended product: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL (Product #89882).
Target Information
The Dedicator of cytokinesis protein 8 (DOCK8) belongs to the DOCK180 family of guanine nucleotide exchange factors.
DOCK8 is essential for humoral immune responses and plays a critical role in B cell immunological synapse formation.
Mutations in DOCK8 cause the autosomal recessive form of hyper-IgE syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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