Thermo Fisher Scientific HMBS Monoclonal Antibody (OTI1F1), TrueMAB
HMBS 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot에 적합합니다. 인간 유래 단백질을 면역원으로 사용하였으며, carrier-free 형태로 제공되어 결합 실험에 유용합니다. 동결건조 상태로 제공되며, 재구성 시 1 mg/mL 농도로 사용 가능합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F1 |
| Immunogen | Full length human recombinant protein of human HMBS produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PBGD (porphobilinogen deaminase), also known as hydroxymethylbilane synthase (HMBS), is a cytoplasmic enzyme involved in the heme synthesis pathway.
PBGD deficiency leads to errors in pyrrole metabolism, resulting in acute intermittent porphyria (AIP), an inherited autosomal disorder characterized by acute neurological dysfunctions such as hypertension, tachycardia, peripheral neuropathy, abdominal pain, and elevated urinary aminolevulinic acid and porphobilinogen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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