Thermo Fisher Scientific Glucocorticoid Receptor Polyclonal Antibody
상품 옵션 정보 | |||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 재고 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA128366 | - | Thermo Fisher Scientific PA128366 Glucocorticoid Receptor Polyclonal Antibody 100 ul pk | 재고문의 | pk | 723,000원 | - | 795,300원 |
Applications
Tested Dilution
Publications
Western Blot (WB)
1:500-1:1,000
Product Specifications
Species Reactivity
Human, Non-human primate
Host/Isotype
Sheep / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide consisting of amino acids 150-175 of squirrel monkey glucocorticoid receptor coupled to diptheria toxoid. This sequence is identical in human glucocorticoid receptor except for 2 amino acids (lowercase): N terminus - APkEKEFPKTHSDVSSEQQnLKGQTG-NH2 if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
Glucocorticoid Receptor (Nr3c1),
uniProtId:
P04150-1,
ncbiNodeId:
9606,
antigenRange:
150-175,
antigenLength:
777,
antigenImageFileName:
PA1-28366_Glucocorticoid_Receptor_Nr3c1_P04150-1_Sheep.svg,
antigenImageFileNamePDP:
PA1-28366_Glucocorticoid_Receptor_Nr3c1_P04150-1_Sheep_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
Conc. Not Determined
Purification
purified
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_1957682
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Glucocorticoid Receptor (NR3C1) is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. Glucocorticoid Receptor can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Glucocorticoid Receptor is expressed in the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. Mutations in the Glucocorticoid Receptor gene are a cause of glucocorticoid resistance, or cortisol, resistance. Studies have shown that glucocorticoid receptor (GR) must be associated with a complex of chaperone proteins for ligand activation. GR binds to known steroids such as dexamethasone with nanomolar affinity
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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