Thermo Fisher Scientific GLI2 Monoclonal Antibody (OTI1G1), TrueMAB
GLI2 단백질을 인식하는 Mouse monoclonal antibody로 Western blot과 IHC(Paraffin) 실험에 적합. 인체 유래 항원을 기반으로 제작되었으며, 고순도의 액상 형태로 제공. PBS, BSA, glycerol buffer에 보관되며 -20°C에서 안정적으로 저장 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 729–1123 of human GLI2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
Gli-2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are transcription factors that bind DNA through zinc finger motifs containing conserved H-C links. Gli family zinc finger proteins mediate Sonic hedgehog (Shh) signaling and act as potent oncogenes in embryonal carcinoma cells. The encoded protein localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It also plays a role during embryogenesis. Mutations in this gene are associated with several phenotypes, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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