Thermo Fisher Scientific NQO1 Polyclonal Antibody
NQO1 단백질을 인식하는 염소 유래 폴리클로날 항체로, 인간 및 흰쥐에 반응합니다. WB, IHC, ICC/IF 등 다양한 응용에 적합하며, 고순도 액상 형태로 제공됩니다. 암 및 알츠하이머 질환 관련 연구용으로 사용됩니다.
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- PA518022
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.3 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 2–4 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide sequence (SIPTDNQIKARK) corresponding to the C-terminus amino acids of NQO1 (aa 263–274) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10982267 |
Product Specific Information
This antibody is predicted to react with porcine and rat based on sequence homology.
Tested in Peptide ELISA with antibody detection limit dilution of 64,000.
Target Information
NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and functions as a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones, preventing the formation of radical species. Altered expression has been observed in various tumors and is associated with Alzheimer’s disease (AD).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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