Thermo Fisher Scientific GABRG1 Polyclonal Antibody
GABRG1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P) 검증 완료. 인간, 생쥐, 랫트 반응성. 항원 친화 크로마토그래피로 정제된 고순도 시약. 신경전달 억제 관련 연구용에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 20–72 of human GABAA R gamma1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553542 |
Product Specific Information
This antibody detects endogenous protein at a molecular weight of approximately 54 kDa.
Purity is >95% by SDS-PAGE.
Target Information
Gabrg1 encodes a protein belonging to the ligand-gated ionic channel family. It is an integral membrane protein that plays a key role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening a chloride channel.
The Gabrg1 gene is clustered with three other family members on chromosome 4.
GABAA receptors are members of the Cys-loop family of ligand-gated ion channels and, along with GABAB receptors, mediate the inhibitory effects of GABA. Structurally, GABAA receptors are pentameric proteins consisting of five subunits from different families.
Diseases associated with GABRG1 include Alcohol Dependence.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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