Thermo Fisher Scientific TLX1 Polyclonal Antibody
Western blot 및 IHC에 적합한 TLX1 폴리클로날 항체로, Human, Mouse, Rat 반응성 확인. Rabbit IgG 기반으로 항원 친화 크로마토그래피로 정제됨. PBS 버퍼에 0.02% sodium azide 포함, 냉장 또는 -20°C 장기보관 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (IHC) | 25 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 16 amino acid peptide near the amino terminus of human TLX1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long-term storage, store at -20°C. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551905 |
Product Specific Information
- A suggested positive control is mouse spleen tissue lysate.
- PA5-34553 can be used with blocking peptide PEP-1596.
Target Information
The Hox proteins play a role in embryonic development and cellular differentiation by regulating downstream target genes. TLX1, also called homeobox11 (HOX11), is a DNA-binding nuclear transcription factor located outside of the four mammalian Hox clusters. It encodes a homeobox-domain containing protein with a glycine and proline-rich amino terminus. TLX1 is required for maintenance of the developing spleen and cell survival. It is highly expressed in T-cell leukemia and lymphoid neoplasias due to translocation. TLX1-deficient mice lack a spleen.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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