Thermo Fisher Scientific alpha Internexin Polyclonal Antibody
신경 발달 초기에 발현되는 alpha-Internexin을 인식하는 Rabbit Polyclonal Antibody로, 인간·마우스·랫트 반응성 확인. WB, ICC/IF, IP 등 다양한 응용 가능. 항원 친화 크로마토그래피로 정제된 고순도 시약. 연구용으로만 사용.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:3,000 |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 |
| Immunoprecipitation (IP) | 1:100–1:800 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human alpha Internexin |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.66 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792760 |
Product Specific Information
- Keep as concentrated solution.
- Predicted reactivity: Mouse (100%), Rat (100%), Rhesus Monkey (100%), Bovine (100%).
- Positive Control: U87-MG, SK-N-SH, SK-N-AS, SH-SY5Y, mouse brain, rat brain.
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
alpha-Internexin is a Class IV intermediate filament subunit expressed very early in neuronal development. It is related to but distinct from the better known neurofilament triplet proteins (NF-L, NF-M, NF-H), having similar protein sequence motifs and intron organization. Many mature neurons contain alpha-Internexin along with NF-L, NF-M, and NF-H, while some express only alpha-Internexin. Antibodies to internexin serve as unique probes to study and classify neuronal types and to trace their processes in sections and tissue culture. Its early developmental expression also makes alpha-Internexin a useful marker for neuronal progenitor cells and cells committed to the neuronal lineage. The use of antibodies to this protein in brain tumor studies remains unexplored but may be of interest.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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