Thermo Fisher Scientific B2M Monoclonal Antibody (OTI1A9), Magnetic beads, TrueMAB
Human beta-2 microglobulin을 인식하는 Mouse monoclonal antibody (clone OTI1A9). Magnetic beads 결합형으로 ELISA 및 Luminex 분석에 적합. 고순도 Affinity chromatography 정제, 안정한 PBS/BSA/glycerol buffer에 보관. 연구용으로만 사용 가능.
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Applications
ELISA (ELISA)
- Tested Dilution: Assay-Dependent
Luminex (LUM)
- Tested Dilution: Assay-Dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1A9 |
| Immunogen | Purified native Human beta 2 Microglobulin protein (UniProt ID: P61769-1, antigen range 1–119) |
| Conjugate | Magnetic beads |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 0.1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Additional Formats
Target Information
Beta-2-microglobulin (B2M) is a 12–14 kDa protein that forms part of the MHC class I complex. It is expressed on various cell types including lymphocytes, monocytes, granulocytes, platelets, endothelial, and epithelial cells but not on erythrocytes. B2M is also found freely in plasma and shares structural homology with immunoglobulin constant regions. It plays roles in antigen presentation and TCR signaling, particularly in naïve CD8+ cells. The B2M gene is located on chromosome 15, and mutations may lead to hypercatabolic hypoproteinemia. B2M levels are useful for assessing renal function and as a prognostic marker in HIV infection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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