Thermo Fisher Scientific HSP70-1A/HSPA1A Monoclonal Antibody (HSPA1A/7932)
HSP70-1A/HSPA1A 단클론 항체로 인간 시료에 반응하며 Western blot 및 IHC(P)에서 사용 가능. 단백질 안정화 및 접힘 연구에 유용. Protein A/G 정제, 액상 형태, 4°C 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 2–4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HSPA1A/7932 |
| Immunogen | Recombinant fragment (around aa200–400) of human HSPA1A protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Colon or testis; human lymph node, kidney
- Cellular Location: Cytoplasm; localized in cytoplasmic mRNP granules containing untranslated mRNAs
Target Information
This intronless gene encodes a 70 kDa heat shock protein, a member of the HSP70 family.
In conjunction with other heat shock proteins, it stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and organelles.
It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1.
The gene is located in the major histocompatibility complex class III region, clustered with two closely related genes encoding similar proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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