Thermo Fisher Scientific HSP70-1A/HSPA1A Monoclonal Antibody (HSPA1A/7936)
HSP70-1A/HSPA1A 단백질을 인식하는 Thermo Fisher monoclonal 항체. Western blot과 IHC(P)에서 사용 가능. Human 시료 반응성, Mouse IgG1 isotype. Protein A/G 정제, 4°C 보관. 세포 내 단백질 안정화 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 2–4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HSPA1A/7936 |
| Immunogen | Recombinant fragment (around aa200–400) of human HSPA1A protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Positive Control: Colon or testis, human lymph node, kidney
- Cellular Location: Cytoplasm. Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Target Information
This intronless gene encodes a 70 kDa heat shock protein, a member of the heat shock protein 70 family. In conjunction with other HSPs, it stabilizes existing proteins against aggregation and assists in folding newly translated proteins in the cytosol and organelles. It also plays a role in the ubiquitin-proteasome pathway through interaction with AU-rich element RNA-binding protein 1.
The gene is located in the major histocompatibility complex class III region, clustered with two related genes encoding similar proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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