Thermo Fisher Scientific TUBGCP4 Polyclonal Antibody, MaxPab

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

Product Specifications

Product Specific Information

Protein Sequence:

MIHELLLALS GYPGSIFTWN KRSGLQVSQD FPFLHPSETS VLNRLCRLGT DYIRFTEFIE QYTGHVQQQD HHPSQQGQGG LHGIYLRAFC TGLDSVLQPY RQALLDLEQE FLGDPHLSIS HVNYFLDQFQ LLFPSVMVVV EQIKSQKIHG CQILETVYKH SCGGLPPVRS ALEKILAVCH GVMYKQLSAW MLHGLLLDQH EEFFIKQGPS SGNVSAQPEE DEEDLGIGGL TGKQLRELQD LRLIEEENML APSLKQFSLR VEILPSYIPV RVAEKILFVG ESVQMFENQN VNLTRKGSIL KNQEDTFAAE LHRLKQQPLF SLVDFEQVVD RIRSTVAEHL WKLMVEESDL LGQLKIIKDF YLLGRGELFQ AFIDTAQHML KTPPTAVTEH DVNVAFQQSA HKVLLDDDNL LPLLHLTIEY HGKEHKDATQ AREGPSRETS PREAPASGWA ALGLSYKVQW PLHILFTPAV LEKYNVVFKY LLSVRRVQAE LQHCWALQMQ RKHLKSNQTD AIKWRLRNHM AFLVDNLQYY LQVDVLESQF SQLLHQINST RDFESIRLAH DHFLSNLLAQ SFILLKPVFH CLNEILDLCH SFCSLVSQNL GPLDERGAAQ LSILVKGFSR QSSLLFKILS SVRNHQINSD LAQLLLRLDY NKYYTQAGGT LGSFGM

Target Information

The gamma-Tubulin complex is composed of gamma Tubulin and the associated proteins GCP2, GCP3, GCP4, GCP5, and GCP6, which are essential for microtubule organizing centers. These components localize to the centrosome for microtubule nucleation and also exist as soluble cytoplasmic complexes.
GCP4 (gamma-Tubulin complex component 4), also known as TUBGCP4, is a 667 amino acid protein expressed ubiquitously and localizes to the metaphase spindle during mitosis. Upon proteasome inhibition, GCP4 accumulates at the pericentriolar material, participating in microtubule organization and nucleation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.